Matrix vesicles are carriers of bone morphogenetic proteins (BMPs), vascular endothelial growth factor (VEGF), and noncollagenous matrix proteins

NN Nahar, LR Missana, R Garimella, SE Tague… - Journal of bone and …, 2008 - Springer
Matrix vesicles (MVs) are well positioned in the growth plate to serve as a carrier of
morphogenetic information to nearby chondrocytes and osteoblasts. Bone morphogenetic
proteins (BMPs) carried in MVs could promote differentiation of these skeletal cells. Vascular
endothelial growth factor (VEGF) in MVs could stimulate angiogenesis. Therefore, a study
was undertaken to confirm the presence of bone morphogenetic protein (BMP)-1 through-7,
VEGF, and the noncollagenous matrix proteins, bone sialoprotein (BSP), osteopontin (OPN) …

Matrix Vesicles are carriers of Bone Morphogenetic Proteins (BMPs)

NN Nahar, LR Missana, R Garimella, SE Tague… - 2008 - ri.conicet.gov.ar
Matrix vesicles (MVs) are well-positioned in the growth plate to serve as a carrier of
morphogenetic information to nearby chondrocytes and osteoblasts. Bone morphogenetic
proteins (BMPs), carried in MVs could promote differentiation of the above skeletal cells.
Vascular endothelial growth factor (VEGF) in MVs could stimulate angiogenesis. Therefore,
a study was undertaken to confirm the presence of bone morphogenetic proteins (BMPs) 1
through 7, VEGF and the non-collagenous matrix proteins, bone sialoprotein (BSP) …
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